Multicentric Osteolysis, Nodulosis, and Arthropathy in Two Unrelated Children with Matrix Metalloproteinase 2 Variants: Genetic-Skeletal Correlations

Clinical Cases

1Hanan Elsebaie Saleh,2Mohamed Abdelhafiz Mansour, 1Solaf M. Elsayed, 1Shady Mahmoud, 1Tamer A. El-Sobky 1Ain Shams University, 2Egyptian Armed Forces Background: Multicentric Osteolysis, Nodulosis, and Arthropathy (MONA) syndrome is a rare genetic skeletal dysplasia. Its diagnosis can be deceptively similar to childhood-onset genetic skeletal dysplasias and juvenile idiopathic arthritis. We aimed to report the syndrome’s clinical…

A Tale of Three Rashes

Clinical Cases

1,2Martin Lee 1Mediclinic Parkview, 2Mohammed Bin Rashid University Background: Skin rashes are commonly an external visible marker of internal disease and are therefore often useful in the diagnosis of a variety of systemic diseases managed by rheumatologists. I present a case of a lady who developed three discrete episodes of different skin rashes over the…

A Case of Pl-7 Positive Amyopathic Dermatomyositis Associated with Autoimmune Liver Disease

Clinical Cases

1,2Martin Lee,3Victoria Scott-Lang, 4Kaiser Raja, 5Sharmishta Sahu 1Mediclinic Parkview, 2Mohammed Bin Rashid University, 3Genesis Healthcare Centre, 4King’s College Hospital, 5Healthbay Polyclinic Background: Amyopathic Dermatomyositis (ADM) is a variant of dermatomyositis (DM) characterized by the presence of pathognomonic skin features of dermatomyositis but without clinical muscle weakness. ADM is believed to account for about 20% of…

A Case of Rheumatoid Arthritis and Hidradenitis Suppurative

Clinical Cases

1Suad Hannawi,1Haifa Hannawi 1Emirates Health Services Background: Rheumatoid arthritis (RA) is a chronic polyarthritis autoimmune disease that has many extra-articular manifestations; including skin manifestations. Hidradenitis suppurativa is a suppurative condition of the apocrine sweat glands associated with induration, scarring, destruction of skin appendages, and sinus formation. Hidradenitis suppurativa had not been reported with RA. in…

Antiphospholipid Syndrome with Diffuse Alveolar Hemorrhage: Case Report

Clinical Cases

1Amna Ahmed Almuhairi,1Aneja Ritu, 1Diab, Sehriban 1Sheikh Shakhbout Medical City Introduction: Diffuse alveolar hemorrhage (DAH) is a rare, potentially fatal presentation of antiphospholipid syndrome (APS) that can be triggered by infections, toxins or other factors. Due to rarity of DAH in APS, no randomized trials exist, and treatment is guided by case reports, case series,…